Gastric submucosal microdialysis in detection of rat stomach ischemia - a comparison of the 3H2O efflux technique with metabolic monitoring
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F10%3A10062016" target="_blank" >RIV/00216208:11150/10:10062016 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15110/10:10213168 RIV/00179906:_____/10:10062016
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Gastric submucosal microdialysis in detection of rat stomach ischemia - a comparison of the 3H2O efflux technique with metabolic monitoring
Original language description
Comparison of microdialysis approaches to measure blood flow in the stomach is lacking. We compared 3H2O efflux technique with biochemical monitoring during temporary celiac artery occlusion in rats. Probes were implanted in the gastric submucosa and perfused with 3H2O; samples were analyzed for beta-activity, glucose, lactate, pyruvate and glycerol. Gastric mucosa and plasma were subjected to morphometry and analysis of myeloperoxidase, thiols and lactatdehydrogenase. The most dramatic responses were observed in lactate/pyruvate and lactate/glucose (%) ratios; the change in 3H2O efflux was less pronounced. 3H2O efflux correlated best with lactate/glucose ratio. A correlation was also found between plasma lactatdehydrogenase and relative glycerol release. Myeloperoxidase, lactatdehydrogenase and histology score were increased by ischemia-reperfusion, macroscopy and plasma thiols remained unchanged. Microdialysis metabolic monitoring is superior to the 3H2O efflux technique.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Physiological Measurement
ISSN
0967-3334
e-ISSN
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Volume of the periodical
31
Issue of the periodical within the volume
10
Country of publishing house
GB - UNITED KINGDOM
Number of pages
14
Pages from-to
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UT code for WoS article
000281726900009
EID of the result in the Scopus database
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