Up-regulation of the Apo/Fas (CD95) complex on neutrophils harvested during cardiac surgery: distinct findings in patients operated on with or without the use of cardiopulmonary bypass

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F10%3A10069732" target="_blank" >RIV/00216208:11150/10:10069732 - isvavai.cz</a>

Alternative codes found

RIV/00179906:_____/10:10069732

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Up-regulation of the Apo/Fas (CD95) complex on neutrophils harvested during cardiac surgery: distinct findings in patients operated on with or without the use of cardiopulmonary bypass

Original language description

In "on-pump" patients, we found an increase in the expression of CD95 median intensity fluorescence (MFI) on granulocytes from a baseline level median=56, (Q 1=45.5, Q3=64) to a median=88, (Q1=62, Q 3=109.5; p{0.01) at the 3rd postoperative day and median=74, (Q1=63, Q3=84.5; p{0.01) at the 7th postoperative day. In "off-pump" patients, granulocyte CD95 MFI was median=55, (Q1=51, Q3=84) before surgery. The significant increase was found on the 3rd postoperative day only; median=90, (Q 1=66; Q3=98; p{0.05). A similar pattern in the CD95 expression was also found if percentage changes of granulocyte CD95 MFI were followed. Moreover, the significantly increased Apo/Fas expression expressed as a percentage change of CD95 MFI was found in "on-pump" patientscompared to "off-pump" patients, both at the 3rd postoperative day (p{0.05) and at the 7th postoperative day (p{0.01).10.1177/0267659110363318

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

<a href="/en/project/NR9090" target="_blank" >NR9090: The use of miniinvasive extracorporeal circuit (mini-CPB) in cardiac surgery</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Perfusion

ISSN

0267-6591

e-ISSN

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Volume of the periodical

25

Issue of the periodical within the volume

1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

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UT code for WoS article

000275458800008

EID of the result in the Scopus database

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