Inhibitory CD200R and proapoptotic CD95/CD95L molecules on innate immunity cells are modulated by cardiac surgery
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F15%3A10315649" target="_blank" >RIV/00216208:11150/15:10315649 - isvavai.cz</a>
Alternative codes found
RIV/00179906:_____/15:10315649
Result on the web
<a href="http://dx.doi.org/10.1177/0267659114558286" target="_blank" >http://dx.doi.org/10.1177/0267659114558286</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1177/0267659114558286" target="_blank" >10.1177/0267659114558286</a>
Alternative languages
Result language
angličtina
Original language name
Inhibitory CD200R and proapoptotic CD95/CD95L molecules on innate immunity cells are modulated by cardiac surgery
Original language description
Cardiac surgery directly initiates a systemic inflammatory response with the activation of both cellular and humoral parts of the immune system. Exaggerated immune system activation is associated with a risk of life-threatening multi-organ dysfunction and increased morbidity and mortality in the postoperative period. The immune system response is regulated and terminated by inhibitory mechanisms, including the regulatory membrane molecules, such as CD200R, CD95, CD95L and soluble sCD200R. We measured the expression of CD95, CD95L, CD200R and sCD200R molecules in granulocyte and monocyte populations in blood samples of 30 patients who underwent coronary artery bypass grafting using cardiopulmonary bypass. Samples collected before surgery, after surgeryand in the postoperative period were analyzed by flow cytometry and ELISA. We found a significant increase in the percentage of granulocytes featuring the anti-inflammatory molecule CD200R after surgery. We presume that these cells were l
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Perfusion
ISSN
0267-6591
e-ISSN
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Volume of the periodical
30
Issue of the periodical within the volume
7
Country of publishing house
GB - UNITED KINGDOM
Number of pages
13
Pages from-to
543-555
UT code for WoS article
000361978000010
EID of the result in the Scopus database
2-s2.0-84942565998