Wireless capsule endoscopy in enteropathy induced by nonsteroidal anti-inflammatory drugs in pigs
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F10%3A10071314" target="_blank" >RIV/00216208:11150/10:10071314 - isvavai.cz</a>
Alternative codes found
RIV/60162694:G44__/10:00002409 RIV/00179906:_____/10:10071314
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Wireless capsule endoscopy in enteropathy induced by nonsteroidal anti-inflammatory drugs in pigs
Original language description
The aim of this study was to evaluate the diagnostic yield of capsule endoscopy in nonsteroidal anti-inflammatory drug (NSAID)-induced enteropathy in pigs. Indomethacin (400 mg/day) was administered orally for 10 days to eight female pigs. Afterwards, capsule endoscopy was performed, using the EndoCapsule system (OlympusOpticalCo., Tokyo, Japan). The following morning, pharmacological euthanasia and immediate autopsy were performed. Small bowel injury compatible with NSAID-induced enteropathy was observed in 7/8 animals. The most common lesions were red spots and erosions. Ulcers and small intestinal bleeding were identified sporadically. Sensitivity and specificity of capsule endoscopy were 83.3% and 95.8%, respectively. Our results indicate that wireless capsule endoscopy is a highly accurate noninvasive method for evaluation of experimental NSAID-induced enteropathy.10.1007/s10620-009-1066-z
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA305%2F08%2F0535" target="_blank" >GA305/08/0535: Interference of probiotics with factors determining pharmacokinetics of drugs</a><br>
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Digestive Diseases and Sciences
ISSN
0163-2116
e-ISSN
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Volume of the periodical
55
Issue of the periodical within the volume
9
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
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UT code for WoS article
000280595500008
EID of the result in the Scopus database
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