Effect of memantine in Alzheimer's disease evaluated by visual-evoked potentials to pattern-reversal, motion-onset, and cognitive stimuli
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F10%3A10081326" target="_blank" >RIV/00216208:11150/10:10081326 - isvavai.cz</a>
Alternative codes found
RIV/00179906:_____/10:10081326
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Effect of memantine in Alzheimer's disease evaluated by visual-evoked potentials to pattern-reversal, motion-onset, and cognitive stimuli
Original language description
Visual evoked potentials (VEPs) to pattern-reversal and motion stimulation as well as visual cognitive potentials (ERPs) were examined in 17 patients with mild to moderate Alzheimer disease before onset of Memantin treatment and after 3 and 6 months of Memantine therapy. The electrophysiological tests were able to prove a significant beneficial effect of Memantine therapy in our group of patients. Improvement of ERPs (shortening of P300 peak latency by at least 20 ms) occurred in 42% of patients. On theother hand, Memantine therapy led in 52% of patients to transitory decline of motion processing (delay of N2 peak latency of the motion-onset VEPs by at least 10 ms after the first 3 months of therapy, followed by return to pre-therapy values in next 3months).
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Clinical Neurophysiology
ISSN
0736-0258
e-ISSN
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Volume of the periodical
27
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
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UT code for WoS article
000282362400005
EID of the result in the Scopus database
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