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Irinotecan induces senescence and apoptosis in colonic cells in vitro

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F12%3A10123424" target="_blank" >RIV/00216208:11150/12:10123424 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.toxlet.2012.08.004" target="_blank" >http://dx.doi.org/10.1016/j.toxlet.2012.08.004</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.toxlet.2012.08.004" target="_blank" >10.1016/j.toxlet.2012.08.004</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Irinotecan induces senescence and apoptosis in colonic cells in vitro

  • Original language description

    The aim of this work was to study effects of irinotecan on normal colonic cells. It was discovered that in normal colonic fibroblasts irinotecan induces apoptosis whereas in normal colonic fibroblasts the premature type of response is premature senescence.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Toxicology Letters

  • ISSN

    0378-4274

  • e-ISSN

  • Volume of the periodical

    214

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    8

  • Pages from-to

    1-8

  • UT code for WoS article

    000309170500001

  • EID of the result in the Scopus database