Transient hyperphosphatasemia in pediatric renal transplant patients - Is there a need for concern and when?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F12%3A10124856" target="_blank" >RIV/00216208:11150/12:10124856 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1111/j.1399-3046.2010.01379.x" target="_blank" >http://dx.doi.org/10.1111/j.1399-3046.2010.01379.x</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/j.1399-3046.2010.01379.x" target="_blank" >10.1111/j.1399-3046.2010.01379.x</a>

Result language

angličtina

Original language name

Transient hyperphosphatasemia in pediatric renal transplant patients - Is there a need for concern and when?

Original language description

TH of infancy and early childhood is characterized by transiently increased S-ALP, predominantly its bone or liver isoforms. There are neither signs of metabolic bone disease or hepatopathy corresponding to the increased S-ALP, nor a common underlying/triggering disease. TH may also occur in children post-renal Tx, which may raise significant concerns and anxiety. We describe four patients aged 2.8-7 yr in whom the TH occurred at 11-34 (median = 28) months after Tx and lasted from 40 to 105 (median = 63) days. No obvious cause/trigger of TH could be found; the clinical status and bone turnover were not altered. In cases of TH post-Tx, we recommend the evaluation of basic biochemical indices and wrist X-ray. If these results are normal, TH is most likely the diagnosis and the S-ALP can be monitored over the next three months without further testing. In patients with persisting TH for more than three months and/or in children with pre-existing or suspected metabolic bone disease, further

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FG - Paediatrics

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Pediatric Transplantation

ISSN

1397-3142

e-ISSN

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Volume of the periodical

16

Issue of the periodical within the volume

1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

5

Pages from-to

"E5"-"E9"

UT code for WoS article

000299154200002

EID of the result in the Scopus database

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