Insight and Hostility as Predictors and Correlates of Nonadherence in the European First Episode Schizophrenia Trial
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F13%3A10135333" target="_blank" >RIV/00216208:11150/13:10135333 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Insight and Hostility as Predictors and Correlates of Nonadherence in the European First Episode Schizophrenia Trial
Original language description
The association of hostility and insight ratings (PANSS items) with medication adherence measured by Hayward scale was investigated in 443 first episode patients diagnosed with schizophrenia, schizoaffective disorder or schizophreniform disorder. The patients took part in the EUFEST study. Prospectively, high hostility score at baseline significantly predicted nonadherence at 1st month of treatment and low insight at baseline significantly predicted nonadherence at months 1, 6 and 12. The increase of hostility and decrease in insight (over 4 points in PANSS ratings) resulted in an additive OR (95% cofidence limits) for both variables of 73, 5 at month 1, OR 276,1 at month 3 and OR 77,6 at month 6. Lack of insight and its decrease appear to have greaterand more stable predictive association with adherence than hostility. The effects of both variables on adherence do not interact.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FL - Psychiatry, sexology
OECD FORD branch
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Result continuities
Project
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Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Clinical Psychopharmacology
ISSN
0271-0749
e-ISSN
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Volume of the periodical
33
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
4
Pages from-to
258-261
UT code for WoS article
000316303700023
EID of the result in the Scopus database
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