Effects of Body Weight Reduction on Plasma Leptin and Adiponectin/Leptin Ratio in Obese Patients With Type 1 Diabetes Mellitus

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F15%3A10291451" target="_blank" >RIV/00216208:11150/15:10291451 - isvavai.cz</a>

Alternative codes found

RIV/00179906:_____/15:10291451 RIV/00216208:11110/15:10291451 RIV/00064165:_____/15:10291451

Result on the web

<a href="http://www.biomed.cas.cz/physiolres/pdf/64/64_221.pdf" target="_blank" >http://www.biomed.cas.cz/physiolres/pdf/64/64_221.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Effects of Body Weight Reduction on Plasma Leptin and Adiponectin/Leptin Ratio in Obese Patients With Type 1 Diabetes Mellitus

Original language description

The aim of this study was to explore the changes in the adipokines leptin and adiponectin in obese patients with type 1 diabetes mellitus (T1DM) who underwent seven days of fasting and 21 days of low-calorie diet (LCD). The plasma leptin and adiponectinconcentrations were measured in 14 obese patients with T1DM at baseline, immediately after 7 days of fasting, and after 21 days of LCD. 13 non-obese patients with T1DM were studied only after an overnight fasting. Bioimpedance technique was used for determination of body composition. Obese T1DM patients lost 6.0 kg (6.0; 6.8) (median, 25 %; 75 %) and decreased their fat tissue after fasting and LCD. Plasma leptin in obese T1DM was significantly higher than in non-obese T1DM patients: 9.10 (5.06; 25.89)vs. 1.71 (1.12; 7.08) microg . l(-1) and transiently decreased immediately after fasting: 3.45 microg . l(-1) (1.47; 7.00), (P<0.05). Adiponectin/leptin ratio in obese T1DM was significantly lower than in non-obese T1DM patients: 0.67 (0.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

<a href="/en/project/NT12287" target="_blank" >NT12287: The role of insulin resistance in the pathogenesis of cardiometabolic risk in diabetes mellitus</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Physiological Research

ISSN

0862-8408

e-ISSN

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Volume of the periodical

64

Issue of the periodical within the volume

2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

8

Pages from-to

221-228

UT code for WoS article

000357409400009

EID of the result in the Scopus database

2-s2.0-84930154665