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Chondrocyte cultivation in hyaluronan-tyramine cross-linked hydrogel

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F15%3A10293970" target="_blank" >RIV/00216208:11150/15:10293970 - isvavai.cz</a>

  • Alternative codes found

    RIV/68081707:_____/15:00457636 RIV/00159816:_____/15:00062970

  • Result on the web

    <a href="http://dx.doi.org/10.1080/00914037.2014.996715" target="_blank" >http://dx.doi.org/10.1080/00914037.2014.996715</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1080/00914037.2014.996715" target="_blank" >10.1080/00914037.2014.996715</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Chondrocyte cultivation in hyaluronan-tyramine cross-linked hydrogel

  • Original language description

    The application of chondrocyte-seeded hydrogels, such as tyramine-substituted hyaluronan, is a highly promising strategy for damaged cartilage treatments. The rheological characteristics of hyaluronan-tyramine derivative scaffold were determined togetherwith the hydrogel swelling, the water uptake, and the morphological characterization. The chondrocytes seeded in hyaluronan-tyramine hydrogel were viable and expressed markers typical for differentiated chondrocytes with no signs of hypertrophy or extensive expression of matrix metalloproteinases. The lyophilized unseeded hyaluronan-tyramine scaffolds were also implantated into trochlea osteochondral defects in rabbits. In conclusion, the hyaluronan-tyramine derivative was proven to be advisable material as a scaffold for cartilage reconstitution.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EI - Biotechnology and bionics

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Polymeric Materials

  • ISSN

    0091-4037

  • e-ISSN

  • Volume of the periodical

    64

  • Issue of the periodical within the volume

    13

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    14

  • Pages from-to

    661-674

  • UT code for WoS article

    000352724100001

  • EID of the result in the Scopus database

    2-s2.0-84928034696