Chondrocyte cultivation in hyaluronan-tyramine cross-linked hydrogel
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F15%3A10293970" target="_blank" >RIV/00216208:11150/15:10293970 - isvavai.cz</a>
Alternative codes found
RIV/68081707:_____/15:00457636 RIV/00159816:_____/15:00062970
Result on the web
<a href="http://dx.doi.org/10.1080/00914037.2014.996715" target="_blank" >http://dx.doi.org/10.1080/00914037.2014.996715</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/00914037.2014.996715" target="_blank" >10.1080/00914037.2014.996715</a>
Alternative languages
Result language
angličtina
Original language name
Chondrocyte cultivation in hyaluronan-tyramine cross-linked hydrogel
Original language description
The application of chondrocyte-seeded hydrogels, such as tyramine-substituted hyaluronan, is a highly promising strategy for damaged cartilage treatments. The rheological characteristics of hyaluronan-tyramine derivative scaffold were determined togetherwith the hydrogel swelling, the water uptake, and the morphological characterization. The chondrocytes seeded in hyaluronan-tyramine hydrogel were viable and expressed markers typical for differentiated chondrocytes with no signs of hypertrophy or extensive expression of matrix metalloproteinases. The lyophilized unseeded hyaluronan-tyramine scaffolds were also implantated into trochlea osteochondral defects in rabbits. In conclusion, the hyaluronan-tyramine derivative was proven to be advisable material as a scaffold for cartilage reconstitution.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EI - Biotechnology and bionics
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Polymeric Materials
ISSN
0091-4037
e-ISSN
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Volume of the periodical
64
Issue of the periodical within the volume
13
Country of publishing house
US - UNITED STATES
Number of pages
14
Pages from-to
661-674
UT code for WoS article
000352724100001
EID of the result in the Scopus database
2-s2.0-84928034696