Chondrocyte Cultivationi in Hyaluronan-Tyramine Cross-Linked Hydrogel
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F15%3A00112166" target="_blank" >RIV/00216224:14310/15:00112166 - isvavai.cz</a>
Result on the web
<a href="https://www.tandfonline.com/doi/abs/10.1080/00914037.2014.996715?journalCode=gpom20" target="_blank" >https://www.tandfonline.com/doi/abs/10.1080/00914037.2014.996715?journalCode=gpom20</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/00914037.2014.996715" target="_blank" >10.1080/00914037.2014.996715</a>
Alternative languages
Result language
angličtina
Original language name
Chondrocyte Cultivationi in Hyaluronan-Tyramine Cross-Linked Hydrogel
Original language description
The application of chondrocyte-seeded hydrogels, such as tyramine-substituted hyaluronan, is a highly promising strategy for damaged cartilage treatments. The rheological characteristics of hyaluronan-tyramine derivative scaffold were determined together with the hydrogel swelling, the water uptake, and the morphological characterization. The chondrocytes seeded in hyaluronan-tyramine hydrogel were viable and expressed markers typical for differentiated chondrocytes with no signs of hypertrophy or extensive expression of matrix metalloproteinases. The lyophilized unseeded hyaluronan-tyramine scaffolds were also implantated into trochlea osteochondral defects in rabbits. In conclusion, the hyaluronan-tyramine derivative was proven to be advisable material as a scaffold for cartilage reconstitution.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10404 - Polymer science
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
ISSN
0091-4037
e-ISSN
1563-535X
Volume of the periodical
64
Issue of the periodical within the volume
13
Country of publishing house
NO - NORWAY
Number of pages
14
Pages from-to
661-674
UT code for WoS article
000352724100001
EID of the result in the Scopus database
2-s2.0-84928034696