Anti-NMDA receptor antibodies in patients with a first episode of schizophrenia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F15%3A10294842" target="_blank" >RIV/00216208:11150/15:10294842 - isvavai.cz</a>
Alternative codes found
RIV/00179906:_____/15:10294842
Result on the web
<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358648/pdf/ndt-11-619.pdf" target="_blank" >http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358648/pdf/ndt-11-619.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2147/NDT.S80746" target="_blank" >10.2147/NDT.S80746</a>
Alternative languages
Result language
angličtina
Original language name
Anti-NMDA receptor antibodies in patients with a first episode of schizophrenia
Original language description
Background: Encephalitis with antibodies against N-methyl-D-aspartate receptor (NMDA-R) is classified as an autoimmune disorder with psychotic symptoms, which are frequently domi-nant. However, it remains unclear how frequently NMDA-R antibodies lead toa condition that mimics psychosis and first-episode schizophrenia. In our work, we investigated the presence of antibodies against NMDA-R in patients with first-episode psychosis (FEP) in comparison with healthy volunteers. Methods: This study included 50 antipsychotic-na?ve patients with FEP (including 21 women) and 50 healthy volunteers (including 21 women). The mean age of the patients was 27.4 (+-7.4) years and that of the healthy controls was 27.0 (+-7.3) years. Antibodies against NMDA-R in the serum were detected by immunofluorescence. Results: None of the investigated patients with an FEP and none of the healthy controls showed positive antibodies against NMDA-Rs. Conclusion: According to results of studies, a small proportion of
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FL - Psychiatry, sexology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neuropsychiatric Disease and Treatment
ISSN
1178-2021
e-ISSN
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Volume of the periodical
11
Issue of the periodical within the volume
2015
Country of publishing house
NZ - NEW ZEALAND
Number of pages
5
Pages from-to
619-623
UT code for WoS article
000350606700002
EID of the result in the Scopus database
2-s2.0-84929149119