The Effect of LDL-Apheresis and Rheohaemapheresis Treatment on Vitamin E

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F15%3A10312538" target="_blank" >RIV/00216208:11150/15:10312538 - isvavai.cz</a>
Alternative codes found
RIV/61389030:_____/15:00446930 RIV/00216208:11160/15:10312538 RIV/00179906:_____/15:10312538
Result on the web
<a href="http://www.jstage.jst.go.jp/article/jnsv/61/2/61_105/_article" target="_blank" >http://www.jstage.jst.go.jp/article/jnsv/61/2/61_105/_article</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3177/jnsv.61.105" target="_blank" >10.3177/jnsv.61.105</a>

Result language
angličtina
Original language name
The Effect of LDL-Apheresis and Rheohaemapheresis Treatment on Vitamin E
Original language description
Lipid apheresis (extracorporeal lipoprotein elimination) is administered to patients with familial hypercholesterolemia who fail to respond to standard therapy. The nature of the treatment process raises the suspicion that it decreases not only cholesterol but also antioxidants. A group of 12 patients (average age 47 +/- 17 y, 4 homozygous and 8 heterozygous individuals) with familial hypercholesterolemia treated by LDL-apheresis or rheohaemapheresis for 3-12 y was included in the study. In addition tocholesterol and triacylglycerol levels, vitamin E and vitamin A and also other markers of antioxidant activity were investigated. Nevertheless, the most important determined parameter was the vitamin E/cholesterol ratio in serum and lipoproteins. The results indicate that both extracorporeal elimination methods are effective and suitable ways to treat severe familial hypercholesterolemia, as the LDL fraction of cholesterol decreased by approximately 77% and 66% following LDL-apheresis an
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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