Omentin-1 plasma levels and cholesterol metabolism in obese patients with diabetes mellitus typ 1: impact of weight reduction

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F15%3A10314096" target="_blank" >RIV/00216208:11150/15:10314096 - isvavai.cz</a>

Alternative codes found

RIV/00179906:_____/15:10314096

Result on the web

<a href="http://www.nature.com/nutd/journal/v5/n11/full/nutd201533a.html" target="_blank" >http://www.nature.com/nutd/journal/v5/n11/full/nutd201533a.html</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/nutd.2015.33" target="_blank" >10.1038/nutd.2015.33</a>

Result language

angličtina

Original language name

Omentin-1 plasma levels and cholesterol metabolism in obese patients with diabetes mellitus typ 1: impact of weight reduction

Original language description

Background: Omentin-1 is an anti-inflammatory adipokine produced preferentially by visceral adipose tissue. Plasma levels of omentin-1 are decreased in obesity and other insulin-resistant states. Insulin resistence contributes to the changes of cholesterol synthesis and absorption as well. The aim of this study was to characterise omentin-1 plasma levels in obese patients with diabetes melltius type 1 during weight reduction, and to elucidate the relationship between cholesterol metabolism and omentin-1. Methods: Plasma levels of omentin-1 were measured in obese type 1 diabetics (n=14, body mass index )30 kg m-2, age 29-62 years) by enzyme-linked immunosorbent assay (BioVendor). Gas chromatography with flame ionisation detector (Fisons Plc.,) was usedto measure squalene and non-cholesterol sterols - markers of cholesterol synthesis and absorption (phase I). Measurements were repeated after 1 month (phase II; 1 week of fasting in the hospital setting and 3 weeks on a diet containing 15

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Nutrition and Diabetes [online]

ISSN

2044-4052

e-ISSN

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Volume of the periodical

5

Issue of the periodical within the volume

November

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

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UT code for WoS article

000368900100001

EID of the result in the Scopus database

2-s2.0-84946563175