Insulin resistance

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F18%3A39912925" target="_blank" >RIV/00216275:25310/18:39912925 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Insulin resistance
Original language description
Insulin resistance is a condition where our body is unable to optimally manage the essential nutrients. Insulin loses its efficiency, it leads to hyperglycemia and lipid metabolism is impaired. In acquired insulin resistance is all caused by obesity. The prevalence of obesity is increasing worldwide nowadays. The insulin resistance precedes diabetes mellitus type 2 and other complications associated with both diabetes and obesity. The aim of this work was to measure concentrations of monounsaturated fatty acids and to find out dependencies with insulin resistance and diabetes mellitus type 2. There were analyzed 21 samples of type 2 diabetics plasma and 17 samples of healthy donors plasma. After lipid extraction from plasma, the lipids were separated by thin layer chromatography into individual classes, derivatized and methyl esters of fatty acids were analyzed by gas chromatograph with flame-ionization detector. The largest changes were observed for stearic, oleic, trans-vaccenic and nervonic acid.
Czech name
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Czech description
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Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Monitorování cizorodých látek v životním prostředí XX. : sborník ze semináře s mezinárodní účastí
ISBN
978-80-7560-154-4
ISSN
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e-ISSN
neuvedeno
Number of pages
10
Pages from-to
51-60
Publisher name
Univerzita Pardubice
Place of publication
Pardubice
Event location
Ovčárna pod Pradědem
Event date
Apr 25, 2018
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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