Odd-numbered fatty acids in type 2 diabetes mellitus

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F18%3A39912926" target="_blank" >RIV/00216275:25310/18:39912926 - isvavai.cz</a>
Result on the web
—
DOI - Digital Object Identifier
—

Result language
angličtina
Original language name
Odd-numbered fatty acids in type 2 diabetes mellitus
Original language description
This work deals with the study of lipid metabolism in type 2 diabetics focusing on changes in odd numbered fatty acid concentrations. Diabetes mellitus is a syndrome of metabolic disorders in which insulin concentrations and secretion is impaired. It shows off as impaired metabolism of glucose, lipids and proteins. The main goal of this work was to measure concentrations of odd numbered fatty acids (ONFA) in healthy individuals and in patients with type 2 diabetes mellitus and to compare those concentrations between both groups with the use of statistical methods. Plasma samples were deproteinized and lipids were extracted into organic solvents. Thin layer chromatography was used to separate 5 lipid fractions. All lipid fractions were derivatized into fatty acid methyl esters and analyzed by a gas chromatograph. ONFA are minor group of fatty acids and their concentrations are lower in type 2 diabetes mellitus. The most significant changes in concentrations were observed at tridecanoic and pentadecanoic acid.
Czech name
—
Czech description
—

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical
Scientific Papers of the University of Pardubice, Series A, Faculty of Chemical Technology
ISSN
1211-5541
e-ISSN
—
Volume of the periodical
24
Issue of the periodical within the volume
November
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
8
Pages from-to
101-108
UT code for WoS article
—
EID of the result in the Scopus database
—

Similar results(10)