Effects of Arginine Supplementation on Amino Acid Profiles in Blood and Tissues in Fed and Overnight Fasted Rats

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F16%3A10323180" target="_blank" >RIV/00216208:11150/16:10323180 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.3390/nu8040206" target="_blank" >http://dx.doi.org/10.3390/nu8040206</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/nu8040206" target="_blank" >10.3390/nu8040206</a>

Result language

angličtina

Original language name

Effects of Arginine Supplementation on Amino Acid Profiles in Blood and Tissues in Fed and Overnight Fasted Rats

Original language description

We evaluated the effect of chronic intake of arginine on amino acid concentrations in blood plasma, liver, kidneys, and soleus and extensor digitorum longus muscles. Rats were fed a standard diet or a high-arginine diet (HAD) for two months. Half of the animals in each group were sacrificed in the fed state, and the other half after overnight fast. HAD increased blood plasma concentrations of urea, creatinine, arginine, and ornithine and decreased most of other amino acids. Arginine and ornithine increased also in muscles and kidneys. In most of examined tissues decreased methionine, phenylalanine, threonine, asparagine, glycine, serine, and taurine. An increase of lysine was observed in both muscle types. After overnight fast the most of the effects of HAD disappeared. It is concluded that enhanced dietary arginine intake alters distribution of almost all amino acids, and that to get a clear picture about the effects of various nutritional interventions some biochemical measurements should be performed both in postprandial and postabsorptive states.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

ED - Physiology

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Nutrients

ISSN

2072-6643

e-ISSN

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Volume of the periodical

8

Issue of the periodical within the volume

4

Country of publishing house

CH - SWITZERLAND

Number of pages

11

Pages from-to

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UT code for WoS article

000374590200029

EID of the result in the Scopus database

2-s2.0-84962860710