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Effects of Epigallocatechin Gallate on Tert-Butyl Hydroperoxide-Induced Mitochondria Dysfunction in Rat Liver Mitochondrial and Hepatocytes

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F16%3A10330051" target="_blank" >RIV/00216208:11150/16:10330051 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.hindawi.com/journals/omcl/2016/7573131/abs/" target="_blank" >https://www.hindawi.com/journals/omcl/2016/7573131/abs/</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1155/2016/7573131" target="_blank" >10.1155/2016/7573131</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Effects of Epigallocatechin Gallate on Tert-Butyl Hydroperoxide-Induced Mitochondria Dysfunction in Rat Liver Mitochondrial and Hepatocytes

  • Original language description

    Epigallocatechin gallate (EGCG) is a green tea antioxidant with adverse effects on rat liver mitochondria and hepatocytes at high doses. Here, we assessed whether low doses of EGCG would protect these systems from damage induced by tert-butyl hydroperoxide (tBHP). Rat liver mitochondria or permeabilized rat hepatocytes were pretreated with EGCG and then exposed to tBHP. Oxygen consumption, mitochondrial membrane potential (MMP), and mitochondrial retention capacity for calcium were measured. First, 50

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Oxidative Medicine and Cellular Longevity

  • ISSN

    1942-0900

  • e-ISSN

  • Volume of the periodical

    2016

  • Issue of the periodical within the volume

    neuvedeno

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    8

  • Pages from-to

  • UT code for WoS article

    000390781300001

  • EID of the result in the Scopus database

    2-s2.0-85008950120