Amniotic fluid pentraxins: Potential early markers for identifying intra-amniotic inflammatory complications in preterm pre-labor rupture of membranes

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F18%3A10369667" target="_blank" >RIV/00216208:11150/18:10369667 - isvavai.cz</a>

Alternative codes found

RIV/00179906:_____/18:10369667

Result on the web

<a href="https://onlinelibrary.wiley.com/doi/epdf/10.1111/aji.12789" target="_blank" >https://onlinelibrary.wiley.com/doi/epdf/10.1111/aji.12789</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/aji.12789" target="_blank" >10.1111/aji.12789</a>

Result language

angličtina

Original language name

Amniotic fluid pentraxins: Potential early markers for identifying intra-amniotic inflammatory complications in preterm pre-labor rupture of membranes

Original language description

In this study, pentraxin 3 (PTX3), C-reactive protein (CRP), and serum amyloid P component (SAP) concentrations in the amniotic fluid of women with preterm pre-labor rupture of membranes (PPROM) were evaluated based on evidence of microbial invasion of the amniotic cavity (MIAC), intra-amniotic inflammation (IAI), and microbial-associated IAI. A total of 149 women with PPROM were included in this study. Amniotic fluid samples were obtained by transabdominal amniocentesis. Amniotic fluid PTX3, SAP, and CRP concentrations were assessed using enzyme-linked immunosorbent assay. PTX3 and CRP concentrations were higher in women with MIAC, IAI, and microbial-associated IAI than in women without these conditions. SAP concentrations were only higher in the presence of IAI and microbial-associated IAI. Amniotic fluid PTX3 concentrations of 11 ng/mL were found to be the best value for identifying the presence of microbial-associated IAI and IAI in women with PPROM. To conclude, amniotic fluid pentraxins are involved in intra-amniotic inflammatory responses in pregnancies complicated by PPROM.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30214 - Obstetrics and gynaecology

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

American Journal of Reproductive Immunology

ISSN

1046-7408

e-ISSN

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Volume of the periodical

79

Issue of the periodical within the volume

5, Spec. Issue

Country of publishing house

DK - DENMARK

Number of pages

11

Pages from-to

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UT code for WoS article

000430386400003

EID of the result in the Scopus database

2-s2.0-85035235737