Amniotic fluid clusterin in pregnancies complicated by the preterm prelabor rupture of membranes

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F17%3A10331874" target="_blank" >RIV/00216208:11150/17:10331874 - isvavai.cz</a>

Alternative codes found

RIV/00179906:_____/17:10331874

Result on the web

<a href="http://www.tandfonline.com/doi/pdf/10.1080/14767058.2016.1255192?needAccess=true" target="_blank" >http://www.tandfonline.com/doi/pdf/10.1080/14767058.2016.1255192?needAccess=true</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/14767058.2016.1255192" target="_blank" >10.1080/14767058.2016.1255192</a>

Result language

angličtina

Original language name

Amniotic fluid clusterin in pregnancies complicated by the preterm prelabor rupture of membranes

Original language description

Objective: The aim of this study was to evaluate clusterin concentrations in amniotic fluid in pregnancies complicated by preterm prelabor rupture of membranes (PPROM) with respect to the presence of the microbial invasion of the amniotic cavity (MIAC), intra-amniotic inflammation (IAI) and microbial-associated IAI. Methods: One hundred thirty-six women with singleton pregnancies complicated by PPROM were included in this study. Amniotic fluid samples were obtained by transabdominal amniocentesis. Amniotic fluid clusterin concentrations were assessed by enzyme-linked immunosorbent assay. MIAC was determined by a non-cultivation approach. IAI was defined as an amniotic fluid bedside interleukin-6 concentration GREATER-THAN OR EQUAL TO745 pg/mL. Microbial-associated IAI was characterized as the presence of both MIAC and IAI. Result: Women with MIAC, IAI and microbial-associated IAI had lower amniotic fluid clusterin concentrations than women without these complications (with MIAC: median 1314 ng/mL versus without MIAC: median 1633 ng/mL, p = 0.003; with IAI: median 1281 ng/mL versus without IAI: median 1575 ng/mL, p = 0.04; with microbial associated-IAI: median 1220 ng/mL versus without microbial-associated IAI: median 1575 pg/mL; p = 0.008). A week negative correlation between amniotic fluid clusterin concentrations and gestational age at sampling was revealed (rho= MINUS SIGN 0.30; p = 0.0005). Conclusions: The presence of MIAC, IAI and microbial-associated IAI was characterized by lower amniotic fluid clusterin concentrations in pregnancies complicated by PPROM.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30214 - Obstetrics and gynaecology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

The Journal of Maternal-Fetal &amp; Neonatal Medicine

ISSN

1476-7058

e-ISSN

—

Volume of the periodical

30

Issue of the periodical within the volume

21

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

2529-2537

UT code for WoS article

000417425100003

EID of the result in the Scopus database

2-s2.0-84996548933