Cervical fluid calreticulin and cathepsin-G in pregnancies complicated by preterm prelabor rupture of membranes

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F18%3A10336825" target="_blank" >RIV/00216208:11150/18:10336825 - isvavai.cz</a>

Alternative codes found

RIV/00179906:_____/18:10336825

Result on the web

<a href="http://dx.doi.org/10.1080/14767058.2017.1288209" target="_blank" >http://dx.doi.org/10.1080/14767058.2017.1288209</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/14767058.2017.1288209" target="_blank" >10.1080/14767058.2017.1288209</a>

Result language

angličtina

Original language name

Cervical fluid calreticulin and cathepsin-G in pregnancies complicated by preterm prelabor rupture of membranes

Original language description

The study aimed to determine the cervical calreticulin and cathepsin-G concentrations in pregnancies complicated by preterm prelabor rupture of membranes (PPROM) with respect to the presence of microbial invasion of the amniotic cavity (MIAC) and intra-amniotic inflammation (IAI). Eighty women with singleton pregnancies complicated by PPROM were included in this study. Cervical and amniotic fluids were obtained at the time of admission, and concentrations of calreticulin and cathepsin-G in cervical fluid were determined using ELISA. The MIAC was defined as a positive PCR analysis for Ureaplasma species, Mycoplasma hominis, and/or Chlamydia trachomatis and/or by positivity for the 16S rRNA gene. IAI was defines as amniotic fluid bedside IL-6 concentrations GREATER-THAN OR EQUAL TO 745 pg/mL. Neither women with MIAC nor with IAI had different cervical fluid concentrations of calreticulin (with MIAC: median 18.9 pg/mL vs. without MIAC: median 14.7 pg/mL, p=0.28; with IAI: median 14.3 pg/mL vs. without IAI: median 15.6 pg/mL, p=0.57;) or of cathepsin-G (with MIAC: median 30.7 pg/mL vs. without MIAC: median 24.7 pg/mL, p=0.28; with IAI: median 27.3 pg/mL vs. without IAI: median 25.1 pg/mL, p=0.80) than women without those complications. No associations between amniotic fluid IL-6 concentrations, gestational age at sampling, and cervical fluid calreticulin and cathepsin-G concentrations were found. Cervical fluid calreticulin and cathepsin-G concentrations did not reflect the presence of MIAC or IAI in women with PPROM.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30214 - Obstetrics and gynaecology

Project

<a href="/en/project/NV16-28587A" target="_blank" >NV16-28587A: Non-invasive detection of intraamniotic infection based on identification of dominant bacteria in cervical fluid</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

The Journal of Maternal-Fetal &amp; Neonatal Medicine

ISSN

1476-7058

e-ISSN

—

Volume of the periodical

31

Issue of the periodical within the volume

4

Country of publishing house

GB - UNITED KINGDOM

Number of pages

8

Pages from-to

481-488

UT code for WoS article

000423184500013

EID of the result in the Scopus database

2-s2.0-85014565301