Vitamin D status of very low birth weight infants at birth and the effects of generally recommended supplementation on their vitamin D levels at discharge

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F20%3A10399947" target="_blank" >RIV/00216208:11150/20:10399947 - isvavai.cz</a>
Alternative codes found
RIV/00179906:_____/20:10399947
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=-nb7gShE9A" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=-nb7gShE9A</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/14767058.2019.1586873" target="_blank" >10.1080/14767058.2019.1586873</a>

Result language
angličtina
Original language name
Vitamin D status of very low birth weight infants at birth and the effects of generally recommended supplementation on their vitamin D levels at discharge
Original language description
To evaluate vitamin D status in mothers and their very low birth weight infants (VLBW) at birth (umbilical cord blood) and at discharge with currently recommended supplementation of vitamin D. Ninety-four infants with birth weight less than 1500 g completed the study. The total daily vitamin D intake was 800-1000 IU. We examined 25-hydroxyvitamin-D [25(OH)D] levels in maternal serum before labor, in cord blood, and in infants'serum at discharge. Median (IQR) serum 25(OH)D was 21 (14-36) nmol/l [8(6-15) ng/ml] in cord blood, and 46 (37-60) nmol/l [18(15-24) ng/ml] at discharge. Serum 25(OH)D was <50nmol/L in 71,3% of mothers, in 91,5% of cord blood samples, and in almost 60% of preterm newborns at discharge (after 8 weeks of supplementation). Serum 25(OH)D was <75 nmol/L in 88,3% of mothers, in 97,9% of cord blood samples, and in 91,4% of preterm newborns at discharge. In our cohort, we found that due to the very high prevalence of 25(OH)D deficiency among mothers, the current generally recommended dose of vitamin D (800-1000IU per day) for VLBW infants was unable to improve vitamin D levels above the desired 50 or even 75 nmol/L before discharge.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30209 - Paediatrics

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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