Autoimmune and limbic encephalitis: case series with some atypical variables in clinical practise

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F22%3A10442115" target="_blank" >RIV/00216208:11150/22:10442115 - isvavai.cz</a>
Alternative codes found
RIV/00179906:_____/22:10442115
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=8e1f9qNK8G" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=8e1f9qNK8G</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10072-021-05563-x" target="_blank" >10.1007/s10072-021-05563-x</a>

Result language
angličtina
Original language name
Autoimmune and limbic encephalitis: case series with some atypical variables in clinical practise
Original language description
Autoimmune and limbic encephalitides are still rare diseases characterized by rapid diagnostics and treatment development in recent years. The incidence of anti-N-methyl-D aspartate receptor /NMDAR/ encephalitis in about 1.5 per million person per year, and the incidence of paraneoplastic neurological syndromes /PNS/ including limbic encephalitis /LE/ is about 1.22 per 100 000 person per year (Vogrig et al. J Neurol 267:26-35, 1; Dalmau et al. Ann Neurol 61:25-36, 2). The diagnostic criteria of anti-NMDAR encephalitis are alredy well established (Zuliani et al. Neurol Sci 40:2017-2030, 10). We provide immunological and clinical characteristics of anti-NMDAR encephalitis case series emphasizing unusual association with colon tumour in one case and complete recovery in two cases. Then we report two cases of onconeural and cell surface antibody negative limbic encephalitis /LE/ associated with tumours, seizures, cognitive and behavioural changes resulting in severe cerebellar syndrome and fatal outcome. The clinical characteristics and results of selected paraclinical examinations as electroencephalography /EEG/. magnetic resonance imaging /MRI/ and cerebrospinal fluid /CSF/ analysis are reviewed.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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