Stability of a half-sandwich Os(II) complex with indomethacin-functionalized ligand in the presence of carboxypeptidase A
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F22%3A10453185" target="_blank" >RIV/00216208:11150/22:10453185 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15310/22:73615197
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=94ZcEKQmVv" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=94ZcEKQmVv</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/d2dt01085b" target="_blank" >10.1039/d2dt01085b</a>
Alternative languages
Result language
angličtina
Original language name
Stability of a half-sandwich Os(II) complex with indomethacin-functionalized ligand in the presence of carboxypeptidase A
Original language description
In the presence of carboxypeptidase, the hydrolytically stable complex EOs(eta(6)-pcym)(L2)Cl]PF6 (2) partially released the bioactive substituent indomethacin, bound through the amide bond to the chelating 2-(1,3,4-thiadiazol-2-yl)pyridine-based moiety of L2. Stability in the presence of other relevant biomolecules (GSH, NADH, GMP) and cancer cell viability were also studied.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30100 - Basic medicine
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Dalton Transactions
ISSN
1477-9226
e-ISSN
1477-9234
Volume of the periodical
51
Issue of the periodical within the volume
24
Country of publishing house
GB - UNITED KINGDOM
Number of pages
5
Pages from-to
9213-9217
UT code for WoS article
000806840100001
EID of the result in the Scopus database
2-s2.0-85131968511