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Bisquaternary oximes as reactivators of tabun-inhibited human brain cholinesterases: an in vitro study

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F07%3A00006727" target="_blank" >RIV/00216208:11160/07:00006727 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Bisquaternary oximes as reactivators of tabun-inhibited human brain cholinesterases: an in vitro study

  • Original language description

    We have tested three new promising bisquaternary AChE reactivators: K027, K033 and K048; reactivator K048 (reactivation 40%) surpassed all reactivators tested in this study

  • Czech name

    Biskvarterní oximy jako reaktivátory lidských mozkových cholinesteráz inhibovaných tabunem: in vitro studie

  • Czech description

    Tři nové biskvarterní reaktivátory AChE: K027, K033 a K048 byly testovány na lidské mozkové acetylcholinesteráze inhibované tabunem; nejlepších výsledků bylo dosaženo s látkou K048, která obnovila aktivitu inhibovaného enzymu na 40 % původní aktivity

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/OPUOFVZ200603" target="_blank" >OPUOFVZ200603: A new method of prophylaxis, decontamination, diagnostics and therapy afer intoxication with nerve agents and yperits</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Basic and Clinical Pharmacology and Toxicology

  • ISSN

    1742-7835

  • e-ISSN

  • Volume of the periodical

    101

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    DK - DENMARK

  • Number of pages

    4

  • Pages from-to

    25-28

  • UT code for WoS article

  • EID of the result in the Scopus database