In vitro screening of oxime reactivators on the model of paraoxon-inhibited acetylcholinesterase - SAR study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F10%3A00300568" target="_blank" >RIV/00216208:11160/10:00300568 - isvavai.cz</a>
Alternative codes found
RIV/60162694:G44__/10:00002405
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
In vitro screening of oxime reactivators on the model of paraoxon-inhibited acetylcholinesterase - SAR study
Original language description
Screening of reactivation potency was performed with two concentrations of reactivator using rat brain homogenate as the source of AChE. Results were compared with established reactivators pralidoxime, methoxime, HI-6, trimedoxime and obidoxime. More than 30 novel reactivators performed equal or better reactivation ability of POX-inhibited AChE compared to currently used reactivators. SAR were developed.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ME09086" target="_blank" >ME09086: Development of novel antidotal treatment against organophosphorus pesticides</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Bulletin of the Korean Chemical Society
ISSN
0253-2964
e-ISSN
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Volume of the periodical
31
Issue of the periodical within the volume
6
Country of publishing house
KR - KOREA, REPUBLIC OF
Number of pages
6
Pages from-to
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UT code for WoS article
000279126800030
EID of the result in the Scopus database
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