In vitro analysis of iron chelating activity of flavonoids
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F11%3A10100446" target="_blank" >RIV/00216208:11160/11:10100446 - isvavai.cz</a>
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S0162013411000316" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0162013411000316</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jinorgbio.2011.02.003" target="_blank" >10.1016/j.jinorgbio.2011.02.003</a>
Alternative languages
Result language
angličtina
Original language name
In vitro analysis of iron chelating activity of flavonoids
Original language description
26 flavonoids were analyzed for their iron chelating activity and stability of the formed complexes in four patho/physiologically relevant pH conditions (4.5, 5.5, 6.8, 7.5) and compared with clinically used iron chelator deferoxamine. The study demonstrated that the most effective iron binding site of flavonoids represented 6,7-dihydroxy structure present in baicalein which was not inferior in all tested pH to deferoxamine.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
—
Result continuities
Project
—
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Inorganic Biochemistry
ISSN
0162-0134
e-ISSN
—
Volume of the periodical
105
Issue of the periodical within the volume
5
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
9
Pages from-to
693-701
UT code for WoS article
000290923100014
EID of the result in the Scopus database
—