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The effect of the number of carbohydrate moieties on the azaphthalocyanine properties

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F12%3A10124726" target="_blank" >RIV/00216208:11160/12:10124726 - isvavai.cz</a>

  • Result on the web

    <a href="http://pubs.rsc.org/en/content/articlehtml/2012/dt/c2dt30971h" target="_blank" >http://pubs.rsc.org/en/content/articlehtml/2012/dt/c2dt30971h</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1039/c2dt30971h" target="_blank" >10.1039/c2dt30971h</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The effect of the number of carbohydrate moieties on the azaphthalocyanine properties

  • Original language description

    A series of azaphthalocyanines (AzaPc) bearing one, two, four or eight isopropylidene-protected galactosyl units was prepared by azide-alkyne click reaction or by classical Pc template cyclotetramerization of the corresponding dicyanopyrazine and AzaPc properties important for photodynamic therapy were compared. All compounds absorbed at long wavelengths (above 650 nm) and belonged to strong singlet oxygen producers (Phi(Delta) = 0.58-0.64) retaining significant fluorescence emission (Phi(F) = 0.026-0.23). The only exception was the compound with four isopropyliden-protected galactosyl units where partial aggregation was observed. Removal of protecting groups increased the polar character of all AzaPc. However, only AzaPc bearing eight galactoses was found to be water-soluble (105 mg mL(-1)) but noticeably aggregated in water as well as in organic solvents (DMF, DMSO). Amphiphilic AzaPc bearing one deprotected galactose was incorporated into the lipidic bilayer of liposomes in a nonagg

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CC - Organic chemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GAP207%2F11%2F1200" target="_blank" >GAP207/11/1200: Red emitting photoinduced charge transfer sensors from the group of azaphthalocyanines</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Dalton Transactions

  • ISSN

    1477-9226

  • e-ISSN

  • Volume of the periodical

    41

  • Issue of the periodical within the volume

    35

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    9

  • Pages from-to

    10596-10604

  • UT code for WoS article

    000307592600015

  • EID of the result in the Scopus database