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Benzothiazoles - scaffold of interest for CNS targeted drugs

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F15%3A10292871" target="_blank" >RIV/00216208:11160/15:10292871 - isvavai.cz</a>

  • Alternative codes found

    RIV/60162694:G44__/15:43875336 RIV/62690094:18470/15:50003418 RIV/00179906:_____/15:10292871

  • Result on the web

    <a href="http://benthamscience.com/journals/current-medicinal-chemistry/volume/22/issue/6/page/730/" target="_blank" >http://benthamscience.com/journals/current-medicinal-chemistry/volume/22/issue/6/page/730/</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.2174/0929867322666141212120631" target="_blank" >10.2174/0929867322666141212120631</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Benzothiazoles - scaffold of interest for CNS targeted drugs

  • Original language description

    Benzothiazole compounds represent heterocyclic systems comprising a benzene ring fused with a thiazole ring containing nitrogen and sulphur in its structure. Besides the presence of a benzothiazole core in naturally occurring molecules, synthesized compounds containing a benzothiazole moiety in their structure proved to be a significant class of potential therapeutics, as they exhibit biological effects such as antitumor, antibacterial, antitubercular, antiviral, anthelmintic, antidiabetic and many others. Apart from the aforementioned peripheral or microbial active sites, benzothiazole analogues are also biologically active compounds in the central nervous system, where some approved drugs containing a benzothiazole moiety have already been identifiedand are used in the treatment of various neurological disorders. New benzothiazole molecules are currently under development and are being evaluated for several uses including diagnostics and as therapeutic drug candidates for the treatm

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FR - Pharmacology and apothecary chemistry

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Current Medicinal Chemistry

  • ISSN

    0929-8673

  • e-ISSN

  • Volume of the periodical

    22

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    AE - UNITED ARAB EMIRATES

  • Number of pages

    18

  • Pages from-to

    730-747

  • UT code for WoS article

    000349388600006

  • EID of the result in the Scopus database

    2-s2.0-84931265913