Effect of oral administration of green tea extract in various dosage schemes on oxidative stress status of mice in vivo

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F15%3A10312501" target="_blank" >RIV/00216208:11160/15:10312501 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15110/15:33154999

Result on the web

<a href="http://www.degruyter.com/view/j/acph.2015.65.issue-1/acph-2015-0007/acph-2015-0007.xml" target="_blank" >http://www.degruyter.com/view/j/acph.2015.65.issue-1/acph-2015-0007/acph-2015-0007.xml</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1515/acph-2015-0007" target="_blank" >10.1515/acph-2015-0007</a>

Result language

angličtina

Original language name

Effect of oral administration of green tea extract in various dosage schemes on oxidative stress status of mice in vivo

Original language description

Green tea is a favorite beverage and its extracts are popular components of dietary supplements. The aim of the present in vivo study was to obtain detailed information about the effect of a standard green tea extract (Polyphenon, P), at different doses,on antioxidant enzymes and oxidative stress markers in murine blood, liver, small and large intestine. In all doses, P improved the oxidative stress status via an increased content of plasmatic SH-groups (by 21-67 %). Regarding antioxidant enzymes in tissues, the low dose of P had the best positive effect as it elevated the activity of NADPH quinone reductase in liver and small intestine, thioredoxin reductase in small intestine and hepatic superoxide dismutase. Based on these facts, consumption of green tea seems to be safe and beneficial, while consumption of dietary supplements containing high doses of catechins may disturb oxidative balance by lowering the activity of thioredoxin reductase, glutathione S-transferase, glutathione re

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FR - Pharmacology and apothecary chemistry

OECD FORD branch

—

Project

<a href="/en/project/GBP303%2F12%2FG163" target="_blank" >GBP303/12/G163: Centre of drug-dietary supplements interactions and nutrigenetics</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta Pharmaceutica

ISSN

1330-0075

e-ISSN

—

Volume of the periodical

65

Issue of the periodical within the volume

1

Country of publishing house

HR - CROATIA

Number of pages

9

Pages from-to

65-73

UT code for WoS article

000350879000006

EID of the result in the Scopus database

2-s2.0-84924869339