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Rapid Determination of alpha-Hederin and Hederacoside C in Extracts of Hedera helix Leaves Available in the Czech Republic and Poland

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F15%3A10312549" target="_blank" >RIV/00216208:11160/15:10312549 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Rapid Determination of alpha-Hederin and Hederacoside C in Extracts of Hedera helix Leaves Available in the Czech Republic and Poland

  • Original language description

    Leaf extracts of Hedera helix L. are widely used in the treatment of upper respiratory diseases. The saponins alpha-hederin and hederacoside C are considered to be the main compounds responsible for the biological activity. alpha-Hederin and hederacosideC were determined in H. helix leaf extracts using a fast, simple and validated HPLC method. An XTerra MS C18 column and mobile phase composed of 10 mM ammonium acetate at pH 8.5 (adjusted with triethylamine) and acetonitrile were used for the chromatography at 1.2 ml min(-1). The column was kept at 30 degrees C. Detection was performed at 220 nm. An approach utilizing a basic pH of the aqueous part of the mobile phase enabled analysis in 5 minutes in isocratic mode. The method was validated and used for the quality control of H. helix leaf ethanolic extracts.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FR - Pharmacology and apothecary chemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA15-10781S" target="_blank" >GA15-10781S: On-line hyphenation of automated extraction processes with liquid chromatography for complete sample analysis</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Natural Product Communications

  • ISSN

    1934-578X

  • e-ISSN

  • Volume of the periodical

    10

  • Issue of the periodical within the volume

    9

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    3

  • Pages from-to

    1529-1531

  • UT code for WoS article

    000361868900010

  • EID of the result in the Scopus database

    2-s2.0-84954614057