Endoglin is not expressed with cell adhesion molecules in aorta during atherogenesis in apoE-deficient mice

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F15%3A10312686" target="_blank" >RIV/00216208:11160/15:10312686 - isvavai.cz</a>

Result on the web

<a href="http://www.hh.um.es/Abstracts/Vol_30/30_2/30_2_233.htm" target="_blank" >http://www.hh.um.es/Abstracts/Vol_30/30_2/30_2_233.htm</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.14670/HH-30.233" target="_blank" >10.14670/HH-30.233</a>

Result language

angličtina

Original language name

Endoglin is not expressed with cell adhesion molecules in aorta during atherogenesis in apoE-deficient mice

Original language description

Endoglin (TGF-beta receptor III), has been demonstrated to affect vascular endothelium and atherosclerosis. Moreover, it was also demonstrated that endoglin is involved in inflammation and plays a role in leukocyte adhesion and transmigration in vitro and in vivo but not in atherosclerosis related vessels. In this study, we wanted to evaluate endoglin expression in two different parts of the aorta (heart aortic sinus and ascending aorta) and assess its potential simultaneous expression with cell adhesion molecules in non-atherosclerotic and atherosclerotic aortas of apoE-deficient mice. Ten-week-old female apolipoprotein E-deficient mice on a C57BL/6J background (n=24) were randomly subdivided into three groups and were fed either chow diet (for another two months) or Western type diet (for another two or four months). Immunohistochemical staining of endoglin, VCAM-1 and P-selectin in aortic sinus and ascending aorta was performed. Endoglin expression was detected only in endothelial c

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

—

Project

<a href="/en/project/EE2.3.30.0061" target="_blank" >EE2.3.30.0061: Increasing of the R&D capacity at Charles University through new positions for graduates of doctoral studies</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Histology and Histopathology

ISSN

0213-3911

e-ISSN

—

Volume of the periodical

30

Issue of the periodical within the volume

2

Country of publishing house

ES - SPAIN

Number of pages

12

Pages from-to

233-244

UT code for WoS article

000351201300011

EID of the result in the Scopus database

2-s2.0-84920945088