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Flavonoid metabolite 3-(3-hydroxyphenyl)propionic acid formed by human microflora decreases arterial blood pressure in rats

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F16%3A10327780" target="_blank" >RIV/00216208:11160/16:10327780 - isvavai.cz</a>

  • Result on the web

    <a href="http://onlinelibrary.wiley.com/doi/10.1002/mnfr.201500761/full" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/mnfr.201500761/full</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/mnfr.201500761" target="_blank" >10.1002/mnfr.201500761</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Flavonoid metabolite 3-(3-hydroxyphenyl)propionic acid formed by human microflora decreases arterial blood pressure in rats

  • Original language description

    Oral administration of flavonoids is suggested to have an effects on arterial blood pressure. However, the biovailability of nonmetabolized flavonoids is low, thus this study was aimed at testing of effects of quercetin metabolites on vascular smooth muscle cells in vitro and blood pressure in vivo. Several metabolites relaxed isolated rat aorta. The most active of them, 3-(-3-hydroxyphenyl)propionic acid was also tested in vivo on rats and these experiments confirmed in vitro results.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FR - Pharmacology and apothecary chemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GBP303%2F12%2FG163" target="_blank" >GBP303/12/G163: Centre of drug-dietary supplements interactions and nutrigenetics</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Molecular Nutrition and Food Research

  • ISSN

    1613-4125

  • e-ISSN

  • Volume of the periodical

    60

  • Issue of the periodical within the volume

    5

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    11

  • Pages from-to

    981-991

  • UT code for WoS article

    000375914700002

  • EID of the result in the Scopus database

    2-s2.0-84959377741