Current state of bioanalytical chromatography in clinical analysis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F18%3A10379469" target="_blank" >RIV/00216208:11160/18:10379469 - isvavai.cz</a>
Result on the web
<a href="http://pubs.rsc.org/en/content/articlehtml/2018/an/c7an01807j" target="_blank" >http://pubs.rsc.org/en/content/articlehtml/2018/an/c7an01807j</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/c7an01807j" target="_blank" >10.1039/c7an01807j</a>
Alternative languages
Result language
angličtina
Original language name
Current state of bioanalytical chromatography in clinical analysis
Original language description
Chromatographic methods have become popular in clinical analysis in both routine and research laboratories. The purpose of this review article is to provide an overview of the current state of chromatographic methods, i.e., high-performance liquid chromatography (HPLC), gas chromatography (GC), and supercritical fluid chromatography (SFC), in clinical analysis. The aspects related to method sensitivity, selectivity, analysis time, and throughput have been discussed in detail. Adequate solutions to improve these features have also been presented. HPLC is the most widely used method among the chromatographic methods, whereas GC is dedicated to several specific applications, and SFC is used only marginally certainly due to its only recent comeback to the analytical scene. Based on the literature search, the application fields in clinical analysis are divided into the following groups: drugs, hormones, drugs of abuse, metabolomics, lipidomics, volatile organic compounds, biomarkers and endogenous compounds, proteomics, multi-analyte approches, and others. The important features of these applications have been emphasized.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
The Analyst
ISSN
0003-2654
e-ISSN
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Volume of the periodical
143
Issue of the periodical within the volume
6
Country of publishing house
GB - UNITED KINGDOM
Number of pages
21
Pages from-to
1305-1325
UT code for WoS article
000428030100002
EID of the result in the Scopus database
2-s2.0-85043585778