Antioxidant and Anti-Pollution Effect of Naturally Occurring Carotenoids Astaxanthin and Crocin for Human Skin Protection

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F22%3A10458656" target="_blank" >RIV/00216208:11160/22:10458656 - isvavai.cz</a>

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=.riSwoNEmw" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=.riSwoNEmw</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/slct.202201595" target="_blank" >10.1002/slct.202201595</a>

Result language

angličtina

Original language name

Antioxidant and Anti-Pollution Effect of Naturally Occurring Carotenoids Astaxanthin and Crocin for Human Skin Protection

Original language description

Four in vitro oxidative-stress models were used to study the antioxidant/antipollution effects of all-trans-astaxanthin and crocin compared to synthetic antioxidants. DPPH-scavenging activity of astaxanthin (5 mu M) was 2.4, 1.3, 1.4, 1.1 and 0.9-fold higher than that of alpha-tocopherol (AT), butylhydroxytoluene, butylhydroxyanisole, gallic acid and Trolox, respectively. Crocin scavenged the same radicals amount as butylhydroxytoluene and butylhydroxyanisole. Both carotenoids were more effective at reducing ferric ions than synthetic antioxidants and had a protective effect on the viability of stressed epidermal cells. Reactive oxygen species induced by hydrogen peroxide or cigarette smoke on a skin were quenched with astaxanthin and crocin to approximately the same extent as with AT. ASX was 3.8, 2.3 and 14-fold better singlet oxygen scavenger than Trolox, AT and gallic acid, respectively. The polyunsaturated fatty acids in the astaxanthin&apos; emulsion were 6.5 and 2.5-fold more resistant to oxidation than in the control emulsion and the AT&apos; emulsion, respectively.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30104 - Pharmacology and pharmacy

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

ChemistrySelect

ISSN

2365-6549

e-ISSN

—

Volume of the periodical

7

Issue of the periodical within the volume

28

Country of publishing house

DE - GERMANY

Number of pages

13

Pages from-to

e202201595

UT code for WoS article

000829048100001

EID of the result in the Scopus database

2-s2.0-85134961966