Virosome: An engineered virus for vaccine delivery

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F23%3A10470722" target="_blank" >RIV/00216208:11160/23:10470722 - isvavai.cz</a>

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=RS-xd6ROEU" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=RS-xd6ROEU</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jsps.2023.03.016" target="_blank" >10.1016/j.jsps.2023.03.016</a>

Result language

angličtina

Original language name

Virosome: An engineered virus for vaccine delivery

Original language description

The purpose of immunization is the effective cellular and humoral immune response against antigens. Several studies on novel vaccine delivery approaches such as micro-particles, liposomes &amp; nanoparticles, etc. against infectious diseases have been investigated so far. In contrast to the conventional approaches in vaccine development, a virosomes-based vaccine represents the next generation in the field of immunization because of its balance between efficacy and tolerability by virtue of its mechanism of immune instigation. The versatility of virosomes as a vaccine adjuvant, and delivery vehicle of molecules of different nature, such as peptides, nucleic acids, and proteins, as well as provide an insight into the prospect of drug targeting using virosomes. This article focuses on the basics of virosomes, structure, composition formulation and development, advantages, interplay with the immune system, current clinical status, different patents highlighting the applications of virosomes and their status, recent advances, and research associated with virosomes, the efficacy, safety, and tolerability of virosomes based vaccines and the future prospective.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30104 - Pharmacology and pharmacy

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Saudi Pharmaceutical Journal

ISSN

1319-0164

e-ISSN

2213-7475

Volume of the periodical

31

Issue of the periodical within the volume

5

Country of publishing house

SA - THE KINGDOM OF SAUDI ARABIA

Number of pages

13

Pages from-to

752-764

UT code for WoS article

000991192600001

EID of the result in the Scopus database

2-s2.0-85152674319