Cognitive behavioral therapy in pharmacoresistant obsessive-compulsive disorder

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11210%2F16%3A10326035" target="_blank" >RIV/00216208:11210/16:10326035 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11240/16:10326035

Result on the web

<a href="http://dx.doi.org/10.2147/NDT.S101721" target="_blank" >http://dx.doi.org/10.2147/NDT.S101721</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2147/NDT.S101721" target="_blank" >10.2147/NDT.S101721</a>

Result language

angličtina

Original language name

Cognitive behavioral therapy in pharmacoresistant obsessive-compulsive disorder

Original language description

Background: The aim of the study was to determine whether patients with obsessive-compulsive disorder (OCD) resistant to drug therapy may improve their condition using intensive, systematic cognitive behavioral therapy (CBT) lasting for 6 weeks, and whether it is possible to predict the therapeutic effect using demographic, clinical, and selected psychological characteristics at baseline. Methods: Sixty-six OCD patients were included in the study, of which 57 completed the program. The diagnosis was confirmed using the structured Mini International Neuropsychiatric Interview. Patients were rated using the objective and subjective forms of the Yale-Brown Obsessive Compulsive Scale, objective and subjective forms of the Clinical Global Impression, Beck Anxiety Inventory, Beck Depression Inventory, Dissociative Experiences Scale, 20-item Somatoform Dissociation Questionnaire, and the Sheehan Disability Scale before their treatment, and with subjective Yale-Brown Obsessive Compulsive Scale, objective and subjective Clinical Global Impression, Beck Anxiety Inventory, and Beck Depression Inventory at the end of the treatment. Patients were treated with antidepressants and daily intensive group CBT for the 6-week period. Results: During the 6-week intensive CBT program in combination with pharmacotherapy, there was a significant improvement in patients suffering from OCD resistant to drug treatment. There were statistically significantly decrease in the scores assessing the severity of OCD symptoms, anxiety, and depressive feelings. A lower treatment effect was achieved specifically in patients who 1) showed fewer OCD themes in symptomatology, 2) showed a higher level of somatoform dissociation, 3) had poor insight, and 4) had a higher initial level of overall severity of the disorder. Remission of the disorder was more likely in patients who had 1) good insight, 2) a lower initial level of anxiety, and 3) no comorbid depressive disorder.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

50101 - Psychology (including human - machine relations)

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neuropsychiatric Disease and Treatment

ISSN

1178-2021

e-ISSN

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Volume of the periodical

12

Issue of the periodical within the volume

March

Country of publishing house

NZ - NEW ZEALAND

Number of pages

15

Pages from-to

625-639

UT code for WoS article

000371920300001

EID of the result in the Scopus database

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