Mitochondrial replacement therapy in the light of the Convention on Biomedicine: the outline of a dilemma

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11220%2F18%3A10384032" target="_blank" >RIV/00216208:11220/18:10384032 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Mitochondrial replacement therapy in the light of the Convention on Biomedicine: the outline of a dilemma
Original language description
In recent years, wide media attention has been drawn to the mitochondrial replacement therapy (MRT; or, in journalist jargon, the creation of "the three-parent babies")- The novel technique enables physicians to treat serious hereditary mitochondrial diseases in embryos by replacing the embryo's mitochondria carrying the genetic defect with healthy ones. However, the Convention on Human Rights and Biomedicine prohibits any genetic modification that aims at modifying the genome of any descendants. The mitochondrial DNA is inherited in maternal line; therefore, the use of MRT in embryos of female sex could be inadmissible, while in embryos of male sex it could be permissible. This approach, however, might be considered discriminatory. The article analyses basic legal, biological, and ethical questions that require answers in order to solve the said dilemma.
Czech name
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Czech description
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Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
50501 - Law

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical
Czech Yearbook of Public and Private International Law, česká ročenka mezinárodního práva veřejného a soukromého
ISSN
1805-0565
e-ISSN
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Volume of the periodical
2018
Issue of the periodical within the volume
9
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
16
Pages from-to
280-295
UT code for WoS article
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EID of the result in the Scopus database
2-s2.0-85060819960

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