Evidence for cytochrome P450-dependent covalent binding of antitumor drug ellipticine to DNA
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F00%3A00006302" target="_blank" >RIV/00216208:11310/00:00006302 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Evidence for cytochrome P450-dependent covalent binding of antitumor drug ellipticine to DNA
Original language description
Ellipticine is an antitumor drug interacting with DNA by inteacalation. We demonstrate a covalent binding of this drug after its activation by CYP in vitro, which might be a new mechanism of its antitumoric action
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2000
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Drug Metabolism Review
ISSN
0360-2532
e-ISSN
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Volume of the periodical
2000
Issue of the periodical within the volume
32
Country of publishing house
US - UNITED STATES
Number of pages
1
Pages from-to
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UT code for WoS article
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EID of the result in the Scopus database
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