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Alpha-Naphtofavone acts as activator and reversibile or irreversible inhibitor of rabbit microsomal CYP3A6

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F01%3A00107163" target="_blank" >RIV/00216208:11310/01:00107163 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Alpha-Naphtofavone acts as activator and reversibile or irreversible inhibitor of rabbit microsomal CYP3A6

  • Original language description

    Alpha-naphthoflavone is a known substrate, inhibitor and activator of several cytochromes P450 mainly CYP 3A6. We show that CYP 3A enzymes possess an active center accomodating two or three substrates simultaneously.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA523%2F01%2F0840" target="_blank" >GA523/01/0840: Study of the possible increase of poultry productivity by modulation of cytochrome P450 expression and activity during chicken embryonic and postemb</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2001

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Chemico-Biological Interactions

  • ISSN

    0009-2797

  • e-ISSN

  • Volume of the periodical

    138

  • Issue of the periodical within the volume

    11

  • Country of publishing house

    IE - IRELAND

  • Number of pages

    22

  • Pages from-to

    85-106

  • UT code for WoS article

  • EID of the result in the Scopus database