Separations of Biologically Active Peptides on Zirconia-Based Columns

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F09%3A10000522" target="_blank" >RIV/00216208:11310/09:10000522 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Separations of Biologically Active Peptides on Zirconia-Based Columns
Original language description
In this work, RP-HPLC methods using zirconia-based columns have been developed for the separation of biologically active nonapeptides from the group of vasopressins. Zirconium dioxide is an alternative carrier to silica gel and apart from its excellent stability it offers additional interactions, which are helpful in the separation of ionizable compounds. Chromatographic behavior of the analytes was studied on two zirconia reversed phases, zirconium dioxide modified with polybutadiene (PBD) and polystyrene (PS). The influence of mobile phase composition (namely pH, concentration of the buffer and buffer-to-acetonitrile ratio) and temperature on chromatographic parameters (retention, separation efficiency, resolution and symmetry of peaks) was investigated in detail.
Czech name
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Czech description
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Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
5th Proceedings of the International Students Conference "Modern Analytical Chemistry"
ISBN
978-80-86561-41-7
ISSN
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e-ISSN
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Number of pages
4
Pages from-to
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Publisher name
Charles University in Prague ? Faculty of Science
Place of publication
Praha
Event location
Praha
Event date
Sep 21, 2009
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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