G-protein activity in Percoll-purified plasma membranes, bulk plasma membranes, and low-density plasma membranes isolated from rat cerebral cortex

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F09%3A10000743" target="_blank" >RIV/00216208:11310/09:10000743 - isvavai.cz</a>

Alternative codes found

RIV/67985823:_____/09:00329471

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

G-protein activity in Percoll-purified plasma membranes, bulk plasma membranes, and low-density plasma membranes isolated from rat cerebral cortex

Original language description

This work describe a straightforward method for the isolation of clearly defined plasma membrane preparations from rat brain cortex - Percoll-purified plasma membranes, bulk of plasma membranes and low-density plasma membrane fragments. [35S]GTP?S binding experiments measured in the presence of high concentration of GDP succeeded in the resolution of the agonist-responsive component of total binding. The highest efficacy of baclofen agrees well with the role of GABA and GABA-B receptors in inhibitory signalling of the brain, the order of efficacy of different agonists of opioid receptors was DADLE > DAMGO > U-69593.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Medical Science Monitor

ISSN

1234-1010

e-ISSN

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Volume of the periodical

15

Issue of the periodical within the volume

4

Country of publishing house

PL - POLAND

Number of pages

12

Pages from-to

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UT code for WoS article

000266193900005

EID of the result in the Scopus database

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