CD55 and CD59 protein expression by Apodemus (field mice) sperm in the absence of CD46

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F09%3A10001160" target="_blank" >RIV/00216208:11310/09:10001160 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
CD55 and CD59 protein expression by Apodemus (field mice) sperm in the absence of CD46
Original language description
CD55 and CD59 proteins are broadly distributed on epididymal sperm from Apodemus and Mus with expression on the acrosome, neck and tail. It can be inferred that Apodemus have traded expression of CD46 complement regulatory protein for acrosomal instability, providing a novel molecular basis underlying a genus-specific strategy to increase competitive advantage for sperm in the promiscuous reproductive behaviour of Apodemus. Thus, despite not expressing CD46, Apodemus sperm are protected against complement-mediated injury in the female genital tract by CD55 and CD59.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EG - Zoology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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