Binding of proteins to ultra high molecular weight polyethylene wear particles as a possible mechanism of macrophage and lymphocyte activation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F10%3A10078885" target="_blank" >RIV/00216208:11310/10:10078885 - isvavai.cz</a>

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Binding of proteins to ultra high molecular weight polyethylene wear particles as a possible mechanism of macrophage and lymphocyte activation

Original language description

Binding of 5 human plasma proteins to ultra high molecular weight polyethylene wear particles isolated from hip periprosthetic tissues was studied in vitro. The binding was of clearly hydrophobic nature. This could be a machanism by which polyethylene wear particles trigger macrophages and lymphocytes aktivity and thence initiate aseptic inflammation and cause the failure of total joint replacements.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

—

Project

<a href="/en/project/2B06096" target="_blank" >2B06096: Monitoring and Minimization of Wear of UHMWPE in Total Joint Replacements</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Biomedical Materials Research - Part A

ISSN

1549-3296

e-ISSN

—

Volume of the periodical

95A

Issue of the periodical within the volume

3

Country of publishing house

US - UNITED STATES

Number of pages

6

Pages from-to

—

UT code for WoS article

000283959800032

EID of the result in the Scopus database

—