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Up-regulation and redistribution of protein kinase C-delta in chronically hypoxic heart

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F10%3A10080988" target="_blank" >RIV/00216208:11310/10:10080988 - isvavai.cz</a>

  • Alternative codes found

    RIV/67985823:_____/10:00354866

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Up-regulation and redistribution of protein kinase C-delta in chronically hypoxic heart

  • Original language description

    The increase of PKC-delta expression in rat hearts adapted to chronic hypoxia (CIH) is localized mainly in mitochondrial and sarcolemmal membranes. CIH-induced PKC-delta subcellular redistribution was reversed by acute treatment with its inhibitor rottlerin. Our results are in the line with the view that PKC-delta mediates the cardioprotective effect of chronic hypoxia, probably via its mitochondrial and sarcolemmal targets.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Molecular and Cellular Biochemistry

  • ISSN

    0300-8177

  • e-ISSN

  • Volume of the periodical

    345

  • Issue of the periodical within the volume

    1-2

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    12

  • Pages from-to

  • UT code for WoS article

    000284907100029

  • EID of the result in the Scopus database