Up-regulation and redistribution of protein kinase C-delta in chronically hypoxic heart
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F10%3A10080988" target="_blank" >RIV/00216208:11310/10:10080988 - isvavai.cz</a>
Alternative codes found
RIV/67985823:_____/10:00354866
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Up-regulation and redistribution of protein kinase C-delta in chronically hypoxic heart
Original language description
The increase of PKC-delta expression in rat hearts adapted to chronic hypoxia (CIH) is localized mainly in mitochondrial and sarcolemmal membranes. CIH-induced PKC-delta subcellular redistribution was reversed by acute treatment with its inhibitor rottlerin. Our results are in the line with the view that PKC-delta mediates the cardioprotective effect of chronic hypoxia, probably via its mitochondrial and sarcolemmal targets.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Molecular and Cellular Biochemistry
ISSN
0300-8177
e-ISSN
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Volume of the periodical
345
Issue of the periodical within the volume
1-2
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
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UT code for WoS article
000284907100029
EID of the result in the Scopus database
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