Elevated lactate is a reliable marker pointing to mitochondrial disorders even in children after brief seizures.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F10%3A10081988" target="_blank" >RIV/00216208:11310/10:10081988 - isvavai.cz</a>

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Elevated lactate is a reliable marker pointing to mitochondrial disorders even in children after brief seizures.

Original language description

Lactate and alanine concentration measurement is useful first-line tool in assessing children with suspected mitochondrial disorders. : Our data indicate that examination of B- and CSF-lactate levels can be considered as a determinant of mitochondrial disorders, with an ability to distinguish these patients from the epileptic ones. Our results suggest that there is no effect of short-period tonic-clonic seizures on the significant raise of B-and CSF-lactate concentrations. Determination of alanine levels also has a high specificity to distinguish between mitochondrial and other multisystem disorders.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

—

Project

—

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Journal of Paediatric Neurology

ISSN

1090-3798

e-ISSN

—

Volume of the periodical

2010

Issue of the periodical within the volume

Neuveden

Country of publishing house

GB - UNITED KINGDOM

Number of pages

8

Pages from-to

—

UT code for WoS article

—

EID of the result in the Scopus database

—