Arginine metabolism in Trichomonas vaginalis infected with Mycoplasma hominis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F10%3A10108838" target="_blank" >RIV/00216208:11310/10:10108838 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1099/mic.0.042192-0" target="_blank" >http://dx.doi.org/10.1099/mic.0.042192-0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1099/mic.0.042192-0" target="_blank" >10.1099/mic.0.042192-0</a>

Result language

angličtina

Original language name

Arginine metabolism in Trichomonas vaginalis infected with Mycoplasma hominis

Original language description

Both Mycoplasma hominis and Trichomonas vaginalis utilize arginine as an energy source via the arginine dihydrolase (ADH) pathway. It has been previously demonstrated that M. hominis forms a stable intracellular relationship with I vaginalis; hence, in this study we examined the interaction of two localized ADH pathways by comparing T. vaginalis strain SS22 with the laboratory-generated T. vaginalis strain SS22-MOZ2 infected with M. hominis MOZ2. The presence of M. hominis resulted in an approximately 16-fold increase in intracellular ornithine and a threefold increase in putrescine, compared with control T vaginalis cultures. No change in the activity of enzymes of the ADH pathway could be demonstrated in SS22-MOZ2 compared with the parent SS22, and the increased production of ornithine could be attributed to the presence of M. hominis. Using metabolic flow analysis it was determined that the elasticity of enzymes of the ADH pathway in SS22-MOZ2 was unchanged compared with the parent

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

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Project

<a href="/en/project/IAA501110631" target="_blank" >IAA501110631: Evolution and biogenesis of mitochondria-related organelles: hydrogenosomes and mitosomes</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Microbiology

ISSN

1350-0872

e-ISSN

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Volume of the periodical

156

Issue of the periodical within the volume

12

Country of publishing house

GB - UNITED KINGDOM

Number of pages

10

Pages from-to

3734-3743

UT code for WoS article

000285806200022

EID of the result in the Scopus database

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