Complete sets of monosubstituted cyclomaltohexaoses (alpha-cyclodextrins) as precursors for further synthesis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F11%3A10099132" target="_blank" >RIV/00216208:11310/11:10099132 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.carres.2011.08.011" target="_blank" >http://dx.doi.org/10.1016/j.carres.2011.08.011</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.carres.2011.08.011" target="_blank" >10.1016/j.carres.2011.08.011</a>
Alternative languages
Result language
angličtina
Original language name
Complete sets of monosubstituted cyclomaltohexaoses (alpha-cyclodextrins) as precursors for further synthesis
Original language description
Alkylation of cyclomaltohexaose (alpha-cyclodextrin, alpha-CD) with allyl or cinnamyl bromide, followed by peracetylation of remaining hydroxyl groups and separation of isomers, resulted in the set of peracetylated 2I-O-, 3I-O- and 6I-O-alkylated a-CDs in up to 27% yields. Ozonolysis or oxidative cleavage of peracetylated allyl or cinnamyl derivatives resulted in a complete set of peracetylated 2I-O-, 3I-O- and 6I-Oformylmethyl or carboxymethyl derivatives that are useful precursors for preparation of regioselectively monosubstituted derivatives of alpha-CD. Moreover, a quick method to recognize single 2I-O-, 3I-O- and 6I-Omonosubstituted peracetylated CDs from one another using only their 1H NMR spectra has been proposed.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/KAN200200651" target="_blank" >KAN200200651: Nanoparticulate and supramolecular systems for targeted drug delivery</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Carbohydrate Research
ISSN
0008-6215
e-ISSN
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Volume of the periodical
346
Issue of the periodical within the volume
15
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
2374-2379
UT code for WoS article
000296950400008
EID of the result in the Scopus database
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