Graft survival and cytokine production profile after limbal transplantation in the experimental mouse model

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F11%3A10104098" target="_blank" >RIV/00216208:11310/11:10104098 - isvavai.cz</a>
Alternative codes found
RIV/68378050:_____/11:00355310
Result on the web
<a href="http://dx.doi.org/10.1016/j.trim.2010.11.005" target="_blank" >http://dx.doi.org/10.1016/j.trim.2010.11.005</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.trim.2010.11.005" target="_blank" >10.1016/j.trim.2010.11.005</a>

Result language
angličtina
Original language name
Graft survival and cytokine production profile after limbal transplantation in the experimental mouse model
Original language description
A new model of orthotopic limbal transplantation was established in the mouse. The survival of limbal autografts, allografts and xenografts was characterized according to the clinical criteria, and intragraft cytokine response was determined by a real-time PCR. The results showed that the limbal grafts do not enjoy immune privilege of the eye and are promptly rejected by Th1 or combined Th1 and Th2 type of immune response involving CD4 pozitive cells and iNOS expression. Targeting this pathway may be aneffective way to prevent and treat limbal graft rejection.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EC - Immunology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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