Asymmetric Aza-Morita-Baylis-Hillman-type reactions: The highly enantioselective reaction between unmodified alpha,beta-unsaturated aldehydes and N-acyl imines by organo-co-catalysis

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F11%3A10105142" target="_blank" >RIV/00216208:11310/11:10105142 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1002/adsc.201000951" target="_blank" >http://dx.doi.org/10.1002/adsc.201000951</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/adsc.201000951" target="_blank" >10.1002/adsc.201000951</a>

Result language
angličtina
Original language name
Asymmetric Aza-Morita-Baylis-Hillman-type reactions: The highly enantioselective reaction between unmodified alpha,beta-unsaturated aldehydes and N-acyl imines by organo-co-catalysis
Original language description
The organo-co-catalytic aza-Morita-Baylis-Hillman (MBH)-type reaction between N-carbamate protected imines and alpha,beta-unsaturated aldehydes has been developed. The organic co-catalytic system of proline and DABCO enables the asymmetric synthesis of the corresponding N-Boc- and N-Cbz-protected beta-amino-alpha,beta-alkylidene-aldehydes in good to high yields and up to 99% ee.
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
—

Project
<a href="/en/project/GP203%2F09%2FP193" target="_blank" >GP203/09/P193: Enantioselective synthesis of N- and S-containing heterocycles via organocatalysis: The way for preparation of biologically active compounds.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)